5/29/2025
Last update
5/29/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 25 Reviews
8.1
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**
Top Medical Research Studies
9
We investigated how inositol supplementation could counteract heart issues caused by lithium in mice. Our study involved four groups of mice to explore the varying effects of inositol. One group received lithium alone, another received lithium followed by inositol, a third group had both lithium and inositol from the start, and a control group had no treatment at all.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
Read More
8
ITPP improves heart function in PH
We investigated the effects of myo-inositol trispyrophosphate (ITPP) on rats with pulmonary hypertension (PH), a condition that often leads to serious heart issues. To do this, we injected some rats with monocrotaline to induce PH and treated others with a placebo. For five weeks, we closely monitored their heart function using echocardiograms and other advanced techniques.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
Read More
Most Useful Reviews
9
Returned menstruation
25 people found this helpful
Desperately trying to restore my menstrual cycle for three years, doctors only prescribed hormones. Finally, a gynaecologist diagnosed me with polycystic ovarian syndrome and recommended Inositol—two capsules in the morning and evening on an empty stomach. I also took fish oil, vitamin E, and evening primrose oil. After seven weeks, I experienced a miracle!
Read More
9
Enhanced ovulation
7 people found this helpful
Since being diagnosed with PCOS at 20, I've sought treatment methods. Having taken Inositol for three years, I love this supplement! It has greatly improved my menstrual cycle, leading to frequent ovulation, reduced acne, and an improved metabolism. Notably, Inositol enhances egg quality during ovulation stimulation cycles, which is vital for those with PCOS and insulin resistance.
Read More
9
Polycystic disease improved
7 people found this helpful
I discovered inositol after my gynecologist recommended it to address cycle irregularities caused by hormonal treatments. Within a month of increased dosage, menstruation returned without hormonal intervention. My skin improved, and my hair thickened. After six months, doctors confirmed the absence of polycystic disease, with my cycle stabilising. I currently take 2000 mg daily.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
We investigated how inositol supplementation could counteract heart issues caused by lithium in mice. Our study involved four groups of mice to explore the varying effects of inositol. One group received lithium alone, another received lithium followed by inositol, a third group had both lithium and inositol from the start, and a control group had no treatment at all.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
Read More
8
ITPP improves heart function in PH
We investigated the effects of myo-inositol trispyrophosphate (ITPP) on rats with pulmonary hypertension (PH), a condition that often leads to serious heart issues. To do this, we injected some rats with monocrotaline to induce PH and treated others with a placebo. For five weeks, we closely monitored their heart function using echocardiograms and other advanced techniques.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
Read More
User Reviews
USERS' SCORE
Good
Based on 25 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Returned menstruation
25 people found this helpful
Desperately trying to restore my menstrual cycle for three years, doctors only prescribed hormones. Finally, a gynaecologist diagnosed me with polycystic ovarian syndrome and recommended Inositol—two capsules in the morning and evening on an empty stomach. I also took fish oil, vitamin E, and evening primrose oil. After seven weeks, I experienced a miracle!
Read More
9
Enhanced ovulation
7 people found this helpful
Since being diagnosed with PCOS at 20, I've sought treatment methods. Having taken Inositol for three years, I love this supplement! It has greatly improved my menstrual cycle, leading to frequent ovulation, reduced acne, and an improved metabolism. Notably, Inositol enhances egg quality during ovulation stimulation cycles, which is vital for those with PCOS and insulin resistance.
Read More
9
Polycystic disease improved
7 people found this helpful
I discovered inositol after my gynecologist recommended it to address cycle irregularities caused by hormonal treatments. Within a month of increased dosage, menstruation returned without hormonal intervention. My skin improved, and my hair thickened. After six months, doctors confirmed the absence of polycystic disease, with my cycle stabilising. I currently take 2000 mg daily.
Read More
7.5
Improved skin symptoms
2 people found this helpful
Being in my late 20s with PCOS, I hadn’t had a period for six months, and it affected my self-esteem, leading to depression and acne. Recommended by my sister, Inositol brought back my period within two weeks and has calmed my skin symptoms. It has reignited my hope for the future and marriage despite my previous setbacks.
Read More
9
Mood improvement
1 people found this helpful
This product works! As someone with polycystic disease, I've struggled with irregular periods for two years. Following my doctor's advice, I consumed 2 grams daily, and by the sixth week, my period finally arrived! Additionally, I noticed a decrease in mood swings and hair loss. I didn't experience any side effects and took it alongside vitamin D and Omega-3. This truly effective product would benefit from larger capsules for convenience.
Read More
Frequently Asked Questions
7.5
Prompt period returns
2 people found this helpful
I was diagnosed with PCOS due to irregular menstruation. Various treatments, including Chinese medicine, failed to restore my period until I tried inositol. After taking one tablet in the morning and evening, my period returned within a week. I was pleasantly surprised by the prompt effect. I plan to continue its use as it appears beneficial for diet-related illnesses. The sole drawback is the size of the tablet, which is somewhat difficult to swallow.
9
Improved menstrual cycle
1 people found this helpful
I have been taking inositol for about a year due to irregular menstrual cycles and polycystic ovary syndrome. Since I started taking 2 tablets with folic acid at bedtime, my cycle has stabilised to 29-31 days, which is ideal for me! Ovulation has improved, and I recommend it to anyone with similar cycle issues and polycystic disease.
9
Polycystic disease improved
7 people found this helpful
I discovered inositol after my gynecologist recommended it to address cycle irregularities caused by hormonal treatments. Within a month of increased dosage, menstruation returned without hormonal intervention. My skin improved, and my hair thickened. After six months, doctors confirmed the absence of polycystic disease, with my cycle stabilising. I currently take 2000 mg daily.
9
Returned menstruation
25 people found this helpful
Desperately trying to restore my menstrual cycle for three years, doctors only prescribed hormones. Finally, a gynaecologist diagnosed me with polycystic ovarian syndrome and recommended Inositol—two capsules in the morning and evening on an empty stomach. I also took fish oil, vitamin E, and evening primrose oil. After seven weeks, I experienced a miracle!
9
Enhanced ovulation
7 people found this helpful
Since being diagnosed with PCOS at 20, I've sought treatment methods. Having taken Inositol for three years, I love this supplement! It has greatly improved my menstrual cycle, leading to frequent ovulation, reduced acne, and an improved metabolism. Notably, Inositol enhances egg quality during ovulation stimulation cycles, which is vital for those with PCOS and insulin resistance.
7.5
Improved skin symptoms
2 people found this helpful
Being in my late 20s with PCOS, I hadn’t had a period for six months, and it affected my self-esteem, leading to depression and acne. Recommended by my sister, Inositol brought back my period within two weeks and has calmed my skin symptoms. It has reignited my hope for the future and marriage despite my previous setbacks.
7.5
Ovulation restored
42 people found this helpful
After my doctor prescribed this supplement for my polycystic disease, I observed improvements while avoiding metformin due to its adverse effects on kidneys. Taking it alongside chromium picolinate and berberine helped alleviate symptoms; my hands returned to normal, and it positively impacted my insulin levels. Since starting treatment, I've had restored ovulation.
9
Mood improvement
1 people found this helpful
This product works! As someone with polycystic disease, I've struggled with irregular periods for two years. Following my doctor's advice, I consumed 2 grams daily, and by the sixth week, my period finally arrived! Additionally, I noticed a decrease in mood swings and hair loss. I didn't experience any side effects and took it alongside vitamin D and Omega-3. This truly effective product would benefit from larger capsules for convenience.
7.5
Efficacy proof
1 people found this helpful
Inositol is an effective remedy for Polycystic Ovary Syndrome. Research indicates that it may lower triglyceride and cholesterol levels without affecting HDL cholesterol in metabolic disease patients. Personally, I take two capsules at night for improved sleep quality, and I find I sleep better and feel more rested in less time. I hope this review helps; please rate it as useful.
9
Ovulation restoration
1 people found this helpful
Inositol works wonderfully! I have polycystic disease and follow my doctor's advice for dosage. Now, I experience ovulation! My cycle has normalised, which is impressive considering I previously went six months without a period. The crucial point is to take it under medical supervision—it's essential!
9
We investigated how inositol supplementation could counteract heart issues caused by lithium in mice. Our study involved four groups of mice to explore the varying effects of inositol. One group received lithium alone, another received lithium followed by inositol, a third group had both lithium and inositol from the start, and a control group had no treatment at all.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
8
ITPP improves heart function in PH
We investigated the effects of myo-inositol trispyrophosphate (ITPP) on rats with pulmonary hypertension (PH), a condition that often leads to serious heart issues. To do this, we injected some rats with monocrotaline to induce PH and treated others with a placebo. For five weeks, we closely monitored their heart function using echocardiograms and other advanced techniques.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
References
- L'Abbate S, Nicolini G, Forini F, Lepore E, Marchetti S, et al. Oral supplementation of inositols effectively recovered lithium-induced cardiac dysfunctions in mice. Biomed Pharmacother. 2024;178:117287. 10.1016/j.biopha.2024.117287
- Oknińska M, Paterek A, Grzanka M, Zajda K, Surzykiewicz M, et al. Myo-inositol trispyrophosphate prevents right ventricular failure and improves survival in monocrotaline-induced pulmonary hypertension in the rat. Br J Pharmacol. 2024;181:4050. 10.1111/bph.16482
